Magnesium stearate: cov kev phiv, kev siv, koob tshuaj, thiab lwm yam.

Raws li cov lus qhia nruj heev rau kev xaiv cov chaw, peb tsuas yog txuas rau cov tsev kawm ntawv tshawb fawb, cov chaw tshaj xov xwm muaj npe nrov, thiab, qhov twg muaj, kev tshawb fawb kho mob uas tau tshuaj xyuas los ntawm cov phooj ywg. Thov nco ntsoov tias cov lej hauv cov ntawv kaw (1, 2, thiab lwm yam) yog cov txuas uas tuaj yeem nyem rau cov kev tshawb fawb no.
Cov ntaub ntawv hauv peb cov ntawv tsis yog los hloov kev sib txuas lus tus kheej nrog tus kws kho mob tsim nyog thiab tsis yog siv los ua cov lus qhia kho mob.
Tsab xov xwm no yog raws li cov pov thawj kev tshawb fawb, sau los ntawm cov kws tshaj lij thiab tshuaj xyuas los ntawm peb pab neeg kho xov xwm uas tau kawm tiav. Thov nco ntsoov tias cov lej hauv cov ntawv kaw (1, 2, thiab lwm yam) sawv cev rau cov kev sib txuas uas nyem tau rau cov kev tshawb fawb kho mob uas tau tshuaj xyuas los ntawm cov phooj ywg.
Peb pab neeg muaj cov kws noj haus thiab cov kws qhia txog kev noj haus uas tau sau npe, cov kws qhia kev noj qab haus huv uas tau ntawv pov thawj, nrog rau cov kws tshwj xeeb txog kev ua kom lub cev muaj zog thiab kev cob qhia, cov kws qhia tus kheej thiab cov kws tshwj xeeb txog kev tawm dag zog kom zoo. Lub hom phiaj ntawm peb pab neeg tsis yog tsuas yog kev tshawb fawb kom ntxaws xwb, tab sis kuj yog kev ncaj ncees thiab kev ncaj ncees.
Cov ntaub ntawv hauv peb cov ntawv tsis yog los hloov kev sib txuas lus tus kheej nrog tus kws kho mob tsim nyog thiab tsis yog siv los ua cov lus qhia kho mob.
Ib qho ntawm cov khoom siv ntxiv uas siv ntau tshaj plaws hauv cov tshuaj thiab cov tshuaj ntxiv niaj hnub no yog magnesium stearate. Qhov tseeb, koj yuav nyuaj rau nrhiav cov tshuaj ntxiv hauv khw niaj hnub no uas tsis muaj nws - txawm tias peb tab tom tham txog cov tshuaj ntxiv magnesium, cov enzymes zom zaub mov, lossis lwm yam tshuaj ntxiv uas koj xaiv - txawm hais tias koj yuav tsis pom nws lub npe ncaj qha.
Feem ntau hu ua lwm lub npe xws li "zaub stearate" lossis cov khoom siv xws li "stearic acid", nws pom yuav luag txhua qhov chaw. Ntxiv nrog rau qhov nyob txhua qhov chaw, magnesium stearate kuj yog ib qho ntawm cov khoom xyaw uas muaj kev tsis sib haum xeeb tshaj plaws hauv ntiaj teb cov tshuaj ntxiv.
Qee txoj kev, qhov no zoo ib yam li kev sib cav txog vitamin B17: nws puas yog tshuaj lom lossis kho tau mob qog noj ntshav. Hmoov tsis zoo rau pej xeem, cov kws tshaj lij kev noj qab haus huv ntuj, cov kws tshawb fawb ntawm cov tuam txhab tshuaj ntxiv, thiab cov kws kho mob feem ntau nthuav tawm cov pov thawj sib txawv los txhawb lawv tus kheej lub tswv yim, thiab qhov tseeb nyuaj heev rau nrhiav tau.
Zoo dua yog siv txoj kev xav uas muaj txiaj ntsig zoo rau cov kev sib cav sib ceg no thiab ceev faj tsis txhob koom nrog cov neeg uas muaj kev xav txawv.
Qhov tseem ceeb yog qhov no: Zoo li feem ntau cov khoom sau thiab cov neeg sawv cev bulking, magnesium stearate tsis zoo rau kev noj qab haus huv hauv cov koob tshuaj ntau, tab sis kev noj nws tsis yog qhov txaus ntshai raws li qee qhov qhia vim tias nws feem ntau tsuas yog muaj nyob rau hauv cov koob tshuaj me me xwb.
Magnesium stearate yog cov ntsev magnesium ntawm stearic acid. Yeej, nws yog ib qho tshuaj uas muaj ob hom stearic acid thiab magnesium.
Stearic acid yog ib hom roj fatty acid uas pom muaj nyob rau hauv ntau yam khoom noj, suav nrog cov roj tsiaj thiab cov roj zaub. Cocoa thiab flaxseed yog cov piv txwv ntawm cov khoom noj uas muaj stearic acid ntau.
Tom qab magnesium stearate raug rhuav tshem rov qab mus rau hauv nws cov khoom sib xyaw hauv lub cev, nws cov rog yuav luag zoo ib yam li stearic acid. Magnesium stearate hmoov feem ntau yog siv ua cov khoom noj khoom haus ntxiv, cov khoom noj khoom haus thiab cov khoom ntxiv hauv cov tshuaj pleev ib ce.
Magnesium stearate yog cov khoom xyaw uas siv ntau tshaj plaws hauv kev tsim cov ntsiav tshuaj vim nws yog cov roj nplua nyeem zoo. Nws kuj tseem siv rau hauv cov tshuaj ntsiav, hmoov, thiab ntau yam khoom noj, suav nrog ntau yam khoom qab zib, gummies, tshuaj ntsuab, txuj lom, thiab cov khoom xyaw ci.
Hu ua "tus neeg sawv cev ntws," nws pab ua kom cov txheej txheem tsim khoom sai dua los ntawm kev tiv thaiv cov khoom xyaw kom tsis txhob lo rau cov khoom siv tshuab. Ib qho hmoov sib tov uas npog yuav luag txhua yam tshuaj lossis cov tshuaj ntxiv nrog me me xwb.
Nws kuj tseem siv tau ua emulsifier, nplaum, thickener, anti-caking agent, roj nplua nyeem, tso tus neeg sawv cev thiab defoamer.
Nws tsis yog tsuas yog muaj txiaj ntsig zoo rau kev tsim khoom los ntawm kev tso cai rau kev thauj mus los zoo ntawm cov tshuab uas tsim lawv, tab sis nws kuj ua rau cov ntsiav tshuaj yooj yim dua rau nqos thiab txav mus los ntawm txoj hnyuv. Magnesium stearate kuj yog ib qho khoom siv pabcuam, uas txhais tau tias nws pab txhim kho cov txiaj ntsig kho mob ntawm ntau yam khoom xyaw nquag hauv tshuaj thiab txhawb kev nqus thiab yaj ntawm cov tshuaj.
Muaj ib txhia hais tias lawv muaj peev xwm tsim cov tshuaj lossis cov tshuaj ntxiv uas tsis muaj cov khoom siv xws li magnesium stearate, ua rau muaj lus nug tias vim li cas lawv thiaj siv thaum muaj lwm yam tshuaj ntuj tsim dua. Tab sis qhov no yuav tsis yog qhov tseeb.
Muaj tej yam khoom uas tam sim no tau tsim los nrog lwm yam khoom siv rau magnesium stearate siv cov khoom siv ntuj xws li ascorbyl palmitate, tab sis peb ua qhov no thaum nws muaj txiaj ntsig thiab tsis yog vim peb tau txais kev tshawb fawb tsis raug. Txawm li cas los xij, cov kev xaiv no tsis yog ib txwm muaj txiaj ntsig vim lawv muaj cov yam ntxwv sib txawv.
Tam sim no tsis meej tias puas muaj peev xwm hloov magnesium stearate lossis tsim nyog.
Magnesium stearate tej zaum yuav muaj kev nyab xeeb thaum noj ntau npaum li pom muaj nyob rau hauv cov tshuaj ntxiv thiab cov khoom noj. Qhov tseeb, txawm koj paub lossis tsis paub los xij, koj yuav tsum noj cov multivitamins, roj txiv maj phaub, qe thiab ntses txhua hnub.
Ib yam li lwm cov zaub mov chelated (magnesium ascorbate, magnesium citrate, thiab lwm yam), [nws] tsis muaj cov teebmeem tsis zoo vim nws muaj cov zaub mov thiab cov kua qaub hauv zaub mov (zaub stearic acid uas tsis muaj zog nrog cov ntsev magnesium). Muaj cov tshuaj tsis ruaj khov.
Nyob rau sab tes tod, Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Hauv Tebchaws (NIH) hauv nws daim ntawv tshaj tawm txog magnesium stearate ceeb toom tias cov magnesium ntau dhau yuav ua rau kev sib kis ntawm cov leeg nqaij thiab ua rau qaug zog thiab txo qis kev xav. Txawm hais tias qhov no tsis tshua muaj, Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Hauv Tebchaws (NIH) tshaj tawm:
Txhua xyoo muaj ntau txhiab tus neeg mob uas muaj tus kab mob no, tab sis cov tsos mob hnyav tsis tshua muaj. Feem ntau cov tshuaj lom neeg no tshwm sim tom qab txhaj tshuaj rau hauv cov hlab ntshav ntau teev (feem ntau yog preeclampsia) thiab tuaj yeem tshwm sim tom qab siv tshuaj ntau dhau, tshwj xeeb tshaj yog thaum lub raum tsis ua haujlwm. Tau muaj kev tshaj tawm tias muaj tshuaj lom neeg no tom qab noj tshuaj ntau dhau, tab sis tsis tshua muaj.
Txawm li cas los xij, daim ntawv tshaj tawm tsis tau ua rau txhua tus neeg ntseeg siab. Tsuas yog saib sai sai hauv Google yuav qhia tias magnesium stearate muaj ntau yam kev phiv, xws li:
Vim tias nws yog hydrophilic ("nyiam dej"), muaj cov lus ceeb toom tias magnesium stearate yuav qeeb qeeb qhov kev yaj ntawm cov tshuaj thiab cov tshuaj ntxiv hauv txoj hnyuv. Cov khoom tiv thaiv ntawm magnesium stearate cuam tshuam ncaj qha rau lub cev lub peev xwm los nqus cov tshuaj thiab cov as-ham, ua rau cov tshuaj lossis cov tshuaj ntxiv tsis muaj txiaj ntsig yog tias lub cev tsis tuaj yeem zom nws kom raug.
Ntawm qhov tod tes, kev tshawb fawb uas tau ua los ntawm University of Maryland hais tias magnesium stearate tsis cuam tshuam rau cov tshuaj uas propranolol hydrochloride tso tawm, ib yam tshuaj siv los tswj lub plawv dhia ceev thiab bronchospasm, yog li cov neeg txiav txim plaub tseem tsis tau txiav txim siab txog qhov no.
Qhov tseeb, cov chaw tsim khoom siv magnesium stearate los ua kom cov tshuaj ntsiav sib xws thiab txhawb kev nqus cov tshuaj kom zoo los ntawm kev ncua qhov kev tawg ntawm cov ntsiab lus kom txog thaum nws mus txog txoj hnyuv.
Cov qe ntshav T, ib qho tseem ceeb ntawm lub cev tiv thaiv kab mob uas tawm tsam cov kab mob, tsis raug cuam tshuam ncaj qha los ntawm magnesium stearate, tab sis los ntawm stearic acid, cov khoom xyaw tseem ceeb hauv cov tshuaj excipients.
Nws tau piav qhia thawj zaug hauv xyoo 1990 hauv phau ntawv xov xwm Immunology, qhov twg txoj kev tshawb fawb tseem ceeb no tau qhia txog yuav ua li cas T-dependent immune responses raug suppressed nyob rau hauv lub xub ntiag ntawm stearic acid ib leeg.
Hauv kev tshawb fawb Nyij Pooj uas ntsuas cov khoom siv pabcuam, cov zaub magnesium stearate tau pom tias yog tus pib ntawm kev tsim formaldehyde. Txawm li cas los xij, qhov no yuav tsis txaus ntshai li nws zoo li, vim muaj pov thawj qhia tias formaldehyde pom muaj nyob rau hauv ntau yam txiv hmab txiv ntoo tshiab, zaub thiab cov khoom tsiaj, suav nrog txiv apples, txiv tsawb, spinach, kale, nqaij nyuj thiab txawm tias kas fes.
Yuav kom koj tsis txhob txhawj, magnesium stearate tsim cov formaldehyde tsawg tshaj plaws ntawm txhua yam khoom siv uas tau sim: 0.3 nanograms ib gram ntawm magnesium stearate. Piv txwv li, kev noj cov nceb shiitake qhuav tsim ntau dua 406 milligrams ntawm formaldehyde ib kilogram noj.
Xyoo 2011, Lub Koom Haum Kev Noj Qab Haus Huv Ntiaj Teb tau tshaj tawm ib daim ntawv qhia txog ntau pawg ntawm magnesium stearate tau raug kuab lom nrog cov tshuaj lom neeg uas yuav ua rau muaj kev phom sij, suav nrog bisphenol A, calcium hydroxide, dibenzoylmethane, irganox 1010 thiab zeolite (sodium aluminium silicate).
Vim tias qhov no yog ib qho xwm txheej uas tshwm sim ib leeg xwb, peb tsis tuaj yeem xaus lus ua ntej lub sijhawm tias cov neeg uas noj cov tshuaj ntxiv thiab cov tshuaj uas muaj magnesium stearate yuav tsum ceev faj txog kev ua qias tuaj ntawm cov tshuaj lom.
Tej zaum ib txhia neeg yuav muaj cov tsos mob ua xua tom qab noj cov khoom lossis cov tshuaj ntxiv uas muaj magnesium stearate, uas tuaj yeem ua rau raws plab thiab mob plab. Yog tias koj muaj kev tsis haum tshuaj rau cov tshuaj ntxiv, koj yuav tsum nyeem cov ntawv lo ntawm cov khoom xyaw kom zoo thiab ua me ntsis kev tshawb fawb kom pom cov khoom uas tsis yog ua los ntawm cov tshuaj ntxiv nrov.
Lub Chaw Haujlwm Saib Xyuas Kev Siv Tshuaj Biotechnology Hauv Tebchaws pom zoo kom noj 2500 mg ntawm magnesium stearate ib kilogram ntawm qhov hnyav ntawm lub cev kom muaj kev nyab xeeb. Rau ib tus neeg laus uas hnyav li 150 phaus, qhov no sib npaug rau 170,000 milligrams ib hnub.
Thaum xav txog cov teeb meem tsis zoo ntawm magnesium stearate, nws yog ib qho tseem ceeb uas yuav tsum xav txog "kev vam khom koob tshuaj". Hauv lwm lo lus, tsuas yog kev txhaj tshuaj ntau dhau rau cov kab mob hnyav xwb, qhov kev puas tsuaj ntawm magnesium stearate tsuas yog pom hauv kev tshawb fawb hauv chav kuaj uas cov nas raug yuam kom noj ntau dhau uas tsis muaj tib neeg hauv ntiaj teb no tuaj yeem noj ntau heev.
Xyoo 1980, phau ntawv xov xwm Toxicology tau tshaj tawm cov txiaj ntsig ntawm kev tshawb fawb uas 40 tus nas tau noj zaub mov semisynthetic uas muaj 0%, 5%, 10%, lossis 20% magnesium stearate rau peb lub hlis. Nov yog qhov nws pom:
Yuav tsum nco ntsoov tias cov stearic acid thiab magnesium stearate uas feem ntau siv rau hauv cov ntsiav tshuaj me me xwb. Stearic acid feem ntau yog 0.5–10% ntawm qhov hnyav ntawm cov ntsiav tshuaj, thaum magnesium stearate feem ntau yog 0.25–1.5% ntawm qhov hnyav ntawm cov ntsiav tshuaj. Yog li, ib lub ntsiav tshuaj 500 mg yuav muaj kwv yees li 25 mg ntawm stearic acid thiab kwv yees li 5 mg ntawm magnesium stearate.
Yog haus dej ntau dhau ces yuav ua rau neeg tuag taus, puas yog? Qhov no yog ib qho tseem ceeb uas yuav tsum nco ntsoov vim tias yog magnesium stearate ua rau ib tug neeg raug mob, lawv yuav tsum tau noj ntau txhiab lub tshuaj ntsiav/ntsiav tshuaj ib hnub.


Lub sijhawm tshaj tawm: Tsib Hlis-21-2024