NICE tau pom zoo thawj zaug txog kev kho mob tshiab uas yuav pab tau cov menyuam mos, cov menyuam yaus thiab cov tub ntxhais hluas uas tab tom kho mob qog noj ntshav kom tsis txhob hnov ​​​​​​lus tsis zoo.
Cisplatin yog ib hom tshuaj kho mob qog noj ntshav muaj zog uas siv dav dav los kho ntau hom mob qog noj ntshav rau menyuam yaus. Raws li lub sijhawm dhau mus, cisplatin tuaj yeem sib sau ua ke hauv pob ntseg sab hauv thiab ua rau o thiab puas tsuaj hu ua ototoxicity, uas yog ib qho ua rau pob ntseg tsis hnov ​​lus.
Cov lus pom zoo kawg pom zoo kom siv cov tshuaj anhydrous sodium thiosulfate, tseem hu ua Pedmarqsi thiab tsim los ntawm Norgine, los tiv thaiv kev hnov ​​​​​​lus tsis zoo los ntawm kev siv tshuaj cisplatin rau cov menyuam yaus hnub nyoog 1 hlis txog 17 xyoo uas muaj cov qog nqaij hlav uas tsis tau kis mus rau lwm qhov ntawm lub cev.
Kwv yees li ntawm 60% ntawm cov menyuam yaus uas tau kho nrog cisplatin yuav muaj kev hnov ​​​​​​lus tsis zoo mus tas li, nrog rau 283 tus neeg mob tshiab ntawm kev hnov ​​​​​​lus tsis zoo ototoxic kuaj pom hauv cov menyuam yaus hnub nyoog qis dua 18 xyoo hauv tebchaws Askiv ntawm xyoo 2022 thiab 2023.
Cov tshuaj no, uas yog muab los ntawm tus kws tu mob lossis tus kws kho mob, ua haujlwm los ntawm kev khi rau cisplatin uas tsis tau raug nqus los ntawm cov cell thiab thaiv nws txoj haujlwm, yog li tiv thaiv kev puas tsuaj rau cov cell pob ntseg. Kev siv sodium thiosulfate anhydrous tsis cuam tshuam rau qhov ua tau zoo ntawm cisplatin chemotherapy.
Kwv yees li ntawm thawj xyoo ntawm kev pom zoo rau kev siv cov tshuaj anhydrous sodium thiosulfate, kwv yees li ntawm 60 lab tus menyuam yaus thiab cov tub ntxhais hluas hauv tebchaws Askiv yuav tsim nyog tau txais cov tshuaj no.
Kev hnov ​​​​​​lus tsis zoo vim yog kev kho mob qog noj ntshav tuaj yeem muaj kev cuam tshuam loj heev rau cov menyuam yaus thiab lawv tsev neeg, yog li peb zoo siab uas tuaj yeem pom zoo rau txoj kev kho mob tshiab no.
Qhov no yog thawj cov tshuaj uas tau ua pov thawj tias tiv thaiv thiab txo cov teebmeem ntawm kev hnov ​​​​lus tsis zoo thiab yuav muaj kev cuam tshuam loj heev rau lub neej ntawm cov menyuam yaus thiab cov tub ntxhais hluas.
Helen hais ntxiv tias: "Peb qhov kev pom zoo ntawm txoj kev kho mob tshiab no qhia txog NICE txoj kev cog lus los tsom mus rau qhov tseem ceeb tshaj plaws: xa cov kev kho mob zoo tshaj plaws rau cov neeg mob sai thiab xyuas kom muaj txiaj ntsig zoo rau cov nyiaj them se."
Cov ntaub ntawv los ntawm ob qhov kev sim tshuaj kho mob qhia tau hais tias kev kho mob yuav luag txo tau ib nrab ntawm tus nqi ntawm kev hnov ​​​​​​lus tsis zoo hauv cov menyuam yaus uas tau txais kev kho mob cisplatin chemotherapy. Ib qho kev sim tshuaj kho mob pom tias cov menyuam yaus uas tau txais kev kho mob cisplatin ua raws li anhydrous sodium thiosulfate muaj 32.7% ntawm kev hnov ​​​​​​lus tsis zoo, piv rau 63% ntawm kev hnov ​​​​​​lus tsis zoo hauv cov menyuam yaus uas tau txais kev kho mob cisplatin chemotherapy ib leeg.
Hauv lwm txoj kev tshawb nrhiav, 56.4% ntawm cov menyuam yaus uas tau txais cisplatin ib leeg tau hnov ​​​​​​lus tsis zoo, piv rau 28.6% ntawm cov menyuam yaus uas tau txais cisplatin ua raws li anhydrous sodium thiosulfate.
Cov kev sim kuj qhia tau tias yog tias cov menyuam yaus tau tsim kev hnov ​​​​​​lus tsis zoo, nws feem ntau tsis hnyav dua rau cov neeg uas siv anhydrous sodium thiosulfate.
Cov niam txiv tau hais rau pawg neeg saib xyuas NICE ywj pheej tias yog tias kev hnov ​​​​​​lus tsis zoo tshwm sim los ntawm kev siv tshuaj cisplatin chemotherapy, nws tuaj yeem cuam tshuam rau kev hais lus thiab kev loj hlob lus, nrog rau kev ua haujlwm ntawm tsev kawm ntawv thiab hauv tsev.
Peb zoo siab tshaj tawm tias cov tshuaj tshiab no yuav raug siv rau cov neeg mob hluas uas tab tom kho mob qog noj ntshav kom tiv thaiv kev hnov ​​​​​​lus tsis zoo vim yog kev phiv los ntawm kev siv tshuaj cisplatin chemotherapy.
Ralph hais ntxiv tias: "Peb tos ntsoov yuav pom cov tshuaj no hauv tsev kho mob thoob plaws lub tebchaws thiab vam tias txhua tus menyuam yaus uas yuav tau txais txiaj ntsig los ntawm nws yuav sai sai no tau txais kev kho mob cawm siav no. Peb ua tsaug rau peb cov neeg txhawb nqa rau lawv txoj kev koom tes, uas tau ua rau RNID muab NICE nrog cov tswv yim tseem ceeb thiab pov thawj los pab ua kom cov tshuaj no muaj dav thoob plaws UK. Qhov no yog thawj zaug uas cov tshuaj tau tsim tshwj xeeb los tiv thaiv kev hnov ​​​​​​lus tsis zoo thiab raug pom zoo kom siv rau NHS. Qhov no yog ib qho tseem ceeb uas yuav ua rau cov neeg nqis peev thiab tsim cov kev kho mob rau kev hnov ​​​​​​lus tsis zoo ntseeg siab tias lawv tuaj yeem coj cov tshuaj mus rau kev ua lag luam. "
Kev kho mob yuav muaj nyob rau ntawm NHS hauv tebchaws Askiv hauv peb lub hlis tom qab tshaj tawm cov lus qhia kawg ntawm NICE.
Lub tuam txhab tau nkag mus rau hauv daim ntawv cog lus ua lag luam zais cia los muab cov sodium thiosulfate anhydrous rau National Health Service ntawm tus nqi qis dua.